Regenerative Medicine

 'Blood is a very special juice' (Goethe's Faust) 

Simplified blood consists of plasma the liquid portion and the blood cells (red and white) and platelets. PRP (platelet rich plasma aka 'Vampire Facial") is used for decades in regenerative medicine to aid and support healing in injuries, the use of PRP/i-PRF (injectable Platelet Rich Fibrin) in aesthetics is a newer concept. The procedure requires to harvest some blood into tubes (PRP tube contains additives vs i-PRF is absolutely additive free), spin in a centrifuge for separation (hard spin for PRP, soft spin for i-PRF), to draw up the plasma and platelets. The activated platelets are then injected in different layers of the skin (area dependent) where they release growth factors which stimulate collagen and elastin production and tighten and thicken the skin, smoothing fine lines and wrinkles. PRP and i-PRF both contain healing and regenerative growth factors, i-PRF contains more platelets in addition to leukocytes and mesenchymal stem cells and the fibrin mesh acts as a scaffolding which helps the plasma to last substantially longer = prolonged release and be more effective. 

In our clinic we upgraded and use the advanced autologous i-PRF.

Advantages of i-PRF: 

- Autologous (derived from ones own blood)

- 100 % natural rejuvenation

- Holistic treatment

- NO additives at all!

- Improves skin quality

- Safe alternative for patients not wanting manufactured products injected

- For patients allergic to Hyaluronidase (HA-Filler Dissolvent)

Treatments for:

Face / Neck / Décolleté / Hand Rejuvenation

Stretch Marks / Acne scars

Fine Lines / Wrinkles

Tear Trough (dark under eye circles)

Nasolabial Folds (nose to mouth lines)

Marionettes (below corner of the mouth)

Smokers Lines ('Barcode')

A course of 3 treatments spaced out 4 - 6 weeks apart is recommended with a maintenance treatment every 9 - 12 months (patient dependent). Results are noticeable after about 6 weeks. 

Thinning hair:

Six treatment sessions every 4 - 6 weeks are recommended for hair loss therapy with one maintenance treatment every 3 to 6 months. Visible improvements after 3 to 6 months.

 i-PRF treatments are the most natural and safest treatment in aesthetic medicine using the powerful platelets in your own blood (autologous) with minimal downtime. The results are not immediate and changes will be subtle as natural over time. The treatment will take up to at least one hour depending on treated areas, i-PRF will be injected superficially with a Meso Injector Device and/or into deeper layers of the skin with hypodermic needles or cannula depending on treated area.

Price:

i-PRF from                                 €   350

Course of 3 from (prepaid)     €   900  

Course of 6 from (prepaid)     € 1,750  (pay 5  get 1 free)

Contraindications to i-PRF (not exhaustive):

- Skin cancer or history of

- Chemotherapy

- Blood disorders (i.e. Thrombocytopenia, Hyperfibrinogenemia)

- Active dermatological conditions

- Acute and chronic infections

- Severe metabolic and systemic disorders

- Septicaemia

- Allergy to topical anaesthetics

- Anticoagulation therapy

Some potential side effects (not exhaustive):

- Minimal swelling/mild bruising/redness/itching at injection site up to 3 days

- Bruising at venepuncture site

- Light headache

- Extremely rare are secondary skin infections

- Injury to a nerve and/or muscle as with any type of injection

Pre-treatment advice: 

- Avoid if possible taking any OTC painkiller like Aspirin/Ibuprofen, Alcohol or other blood thinning supplements (Fish Oils, St.

  John's Wort, Vitamins A-E) 48 hours prior to your appointment as these might increase the risk of bruising

- Systemic use of Corticosteroids within 2 weeks of the procedure

- For your treatment arrive with no make-up

- You should arrive well hydrated

- You should not have had any other aesthetic treatments or vaccines within 2 weeks prior to your appointment.

Post treatment instructions:  

- Avoid massage or put pressure on injected areas for 24 hours

- Avoid any heat i.e. hot showers/baths/sauna/steam/sun exposure/excessive exercises until redness and any swelling has

   resolved

- No alcohol for 48 hours post treatment

- Do not get any other aesthetic treatments or vaccines for at least 2 weeks after your treatment.

Results:

Generally visible at ca. 4 weeks and continue to improve gradually over ensuing 3 - 6 months with improvement in texture and tone. 

Longevity: 

Variable as patient dependant (data shows that results may last up to 18 months)

NB

In whatever case you experience any unexpected symptoms please contact the clinic.

Bio Plasma Gel Filler is an advanced autologous treatment, utilising the patient's own blood plasma for the stimulation and acceleration of tissue healing and regeneration. After having harvested some blood and spun in the centrifuge the platelet poor plasma (PPP) then is heated and cooled down, mixed with liquid PRF and is ready to be injected with needles or micro cannula. This Bio Plasma Gel Filler can be used for either a complete facial restoration or specific areas of concern. It provides an immediate filler effect because of its gel-like consistency.

Benefits:

• Excellent cell bio compatibility and safety profile as autologous
• Natural alternative to synthetic fillers
• For patients allergic to Hyaluronidase (HA filler Dissolvent)
• Stimulates fibroblasts / Increases collagen and elastin / Tissue regeneration
• Wound healing benefits
• Strengthens the skin's barrier function
• Promotes cellular regeneration and skin health
• Dissolves smoothly over time (about three months) and leaves new generated collagen and elastin

 Treatments for:

• Volume loss
• `Creases / Fine lines / Wrinkles
• Plump recessed scars
• Enhance cheek / jawline / chin
• Dark under eye circles (TT)
• Nose to lip lines (NLF) / Marionettes
• Improvement of skin laxity / skin tone / skin texture

A course of 2 - 3 treatments are recommended ca. 8 weeks apart and results are immediately visible. Results can last up to 12 months depending on factors as skin condition, lifestyle, treatment area etc. Recovery time 2 - 7 days. One maintenance treatment every 9 - 12 months is recommended.

Price for full face: 

One session                              €   350      ( a minimum of 5 ml can be obtained)

Course of 2 (prepaid)              €   650

Course of 3 (prepaid)              € 1,200 

Contraindications for Bio Plasma Gel Filler (not exhaustive):

- Skin cancer or history of

- Chemotherapy

- Blood disorders (i.e. Thrombocytopenia, Hyperfibrinogenemia)

- Active dermatological conditions

- Acute and chronic infections

- Severe metabolic and systemic disorders

- Septicaemia

- Allergy to topical anaesthetics

- Anticoagulation therapy

Some potential side effects (not exhaustive):

- Minimal swelling/mild bruising/redness/itching at injection site up to 7 days

- Bruising at venepuncture site

- Light headache

- Extremely rare are secondary skin infections

- Injury to a nerve and/or muscle as with any type of injection

Pre-treatment advice: 

- Avoid if possible taking any OTC painkiller like Aspirin/Ibuprofen, Alcohol or other blood thinning supplements (Fish Oils, St.

  John's Wort, Vitamins A-E) for at least 72 hours prior to your appointment as these might increase the risk of bruising

- No systemic use of Corticosteroids within 2 weeks of the procedure

- For your treatment arrive with no make-up

- You should arrive well hydrated, increase the daily amount of water you drink at least 48 hours prior to your appointment

- You should not have had any other aesthetic treatments or vaccines within 2 weeks prior to your appointment.

Post treatment instructions:  

- Avoid massage or put pressure on injected areas for 24 hours

- Avoid any heat i.e. hot showers/baths/sauna/steam/sun exposure/excessive exercises until redness and any swelling has

   resolved

- No alcohol for 48 hours post treatment

- Keep very well hydrated with water for another week at least

- Do not get any other aesthetic treatments or vaccines for at least 2 weeks after your treatment.

Results:

Generally visible immediately and continue to improve gradually over ensuing 1 - 3 months.

NB

In whatever case you experience any unexpected symptoms please contact the clinic.

Polynucleotides commonly referred to as PN or PDRN (polydeoxyribonucleotide) are fragments of DNA that play crucial roles in cellular repair and regeneration. Polynucleotides are derived from freshwater fish (salmon or trout) are highly purified, ensuring compatibility with human DNA. In aesthetic applications PN is often utilised for skin rejuvenation, hair restoration and wound healing due to its ability to stimulate collagen production, enhance tissue repair and promote overall skin health. Clinical studies have shown promising results including improved skin texture, reduced wrinkles and increased skin hydration. 

PhilArt is manufactured by Croma-Pharma an Austrian company that uses PN-HPT® (Polynucleotides High Purification Technology) featuring a high degree of purification. The European based production facility provides total control of the manufacturing chain ensuring the safety of its products. PhilArt has proven efficacy supported by extensive clinical data.

PhilArt Skin Enhancement Technique (SET) has an important role for the skin quality, restoring radiance and youthfulness, promoting regeneration and reducing wrinkles and laxity. SET generates a synergistic effect with other aesthetic procedures.

PhilArt gels are highly biocompatible with a very low risk of adverse effects.

Recommended is a course of 3 treatments, 2 - 3 weeks apart. Longevity may last up to 6 - 12 months (patient dependant).

PhilArt eye for the delicate skin around the eyes

PhilArt hair to treat scalp and eye brows

€ 250    per treatment / 2 ml syringe

€ 450   course of 2 treatments (prepaid)

€ 650   course of 3 treatments (prepaid)

Procedure time: up to 30 minutes (depending on treatment area) 

Contraindication:  - Fish allergies

                                    - Vegan /(Vegetarian)

Some potential side effects (not exhaustive):

- Stinging / Bleeding as with any type of injection

- Minimal swelling/mild bruising/redness/itching at injection site up to a few days

- Extremely rare are secondary skin infections

- Injury to a nerve and/or muscle as with any type of injection

Pre-treatment advice: 

- Avoid if possible taking any OTC painkiller like Aspirin/Ibuprofen, Alcohol or other blood thinning supplements (Fish Oils, St.

  John's Wort, Vitamins A-E) 48 hours prior to your appointment as these might increase the risk of bruising

- For your treatment arrive with no make-up

- You should not have had any other aesthetic / dental treatments or vaccines within 2 weeks prior to your appointment.

Post treatment instructions:  

- Avoid massage or put pressure on injected areas for 24 hours

- Avoid any heat i.e. hot showers/baths/sauna/steam/sun exposure/excessive exercises until redness and any swelling has

   resolved

- No alcohol for 48 hours post treatment

- Do not get any other aesthetic / dental treatments or vaccines for at least 2 weeks after your treatment.